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Altered translation initiation of Gja1 limits gap junction formation during epithelial–mesenchymal transition

Epithelial–mesenchymal transition (EMT) is activated during development, wound healing, and pathologies including fibrosis and cancer metastasis. Hallmarks of EMT are remodeling of intercellular junctions and adhesion proteins, including gap junctions. The GJA1 mRNA transcript encoding the gap junct...

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Detalles Bibliográficos
Autores principales: James, Carissa C., Zeitz, Michael J., Calhoun, Patrick J., Lamouille, Samy, Smyth, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905293/
https://www.ncbi.nlm.nih.gov/pubmed/29467255
http://dx.doi.org/10.1091/mbc.E17-06-0406