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Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus

RNA-editing mechanisms, which induce nucleotide substitution in the RNA, increase transcript and protein diversities. Editing dysregulation has been shown to lead to grave outcomes, and transcriptome-wide aberrant RNA editing has been found in tumors. However, little is known about the involvement o...

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Detalles Bibliográficos
Autores principales: Roth, Shalom Hillel, Danan-Gotthold, Miri, Ben-Izhak, Meirav, Rechavi, Gideon, Cohen, Cyrille J., Louzoun, Yoram, Levanon, Erez Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905401/
https://www.ncbi.nlm.nih.gov/pubmed/29617672
http://dx.doi.org/10.1016/j.celrep.2018.03.036