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Expression of pyruvate kinase M2 in human bladder cancer and its correlation with clinical parameters and prognosis
BACKGROUND: Pyruvate kinase M2 (PKM2) is a key regulator of the Warburg effect and has critical functions in glycolysis, contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis, and apoptosis. The high expression of PKM2 in various solid tumors renders it a potentia...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905464/ https://www.ncbi.nlm.nih.gov/pubmed/29695915 http://dx.doi.org/10.2147/OTT.S152999 |