Expression of pyruvate kinase M2 in human bladder cancer and its correlation with clinical parameters and prognosis

BACKGROUND: Pyruvate kinase M2 (PKM2) is a key regulator of the Warburg effect and has critical functions in glycolysis, contributing to the Warburg effect, tumor growth, angiogenesis, cell division, metastasis, and apoptosis. The high expression of PKM2 in various solid tumors renders it a potentia...

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Detalles Bibliográficos
Autores principales: Huang, Changkun, Huang, Zhichao, Bai, Peiming, Luo, Guangcheng, Zhao, Xiaokun, Wang, Xinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905464/
https://www.ncbi.nlm.nih.gov/pubmed/29695915
http://dx.doi.org/10.2147/OTT.S152999

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