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Increase in spleen volume as a predictor of oxaliplatin toxicity

BACKGROUND: Oxaliplatin is a nonconventional third-generation platinum compound. It is an important chemotherapeutic agent in regimens used in gastrointestinal carcinomas as well as other malignancies. Oxaliplatin toxicity profile includes neurotoxicity, hepatotoxicity, and splenomegaly. The primary...

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Detalles Bibliográficos
Autores principales: El Chediak, Alissar, Haydar, Ali A, Hakim, Ayman, Massih, Sarah Abdel, Hilal, Lara, Mukherji, Deborah, Temraz, Sally, Shamseddine, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905497/
https://www.ncbi.nlm.nih.gov/pubmed/29695909
http://dx.doi.org/10.2147/TCRM.S150968