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DeepSF: deep convolutional neural network for mapping protein sequences to folds

MOTIVATION: Protein fold recognition is an important problem in structural bioinformatics. Almost all traditional fold recognition methods use sequence (homology) comparison to indirectly predict the fold of a target protein based on the fold of a template protein with known structure, which cannot...

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Detalles Bibliográficos
Autores principales: Hou, Jie, Adhikari, Badri, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905591/
https://www.ncbi.nlm.nih.gov/pubmed/29228193
http://dx.doi.org/10.1093/bioinformatics/btx780