Calpain 3 and CaMKIIβ signaling are required to induce HSP70 necessary for adaptive muscle growth after atrophy

Mutations in CAPN3 cause autosomal recessive limb girdle muscular dystrophy 2A. Calpain 3 (CAPN3) is a calcium dependent protease residing in the myofibrillar, cytosolic and triad fractions of skeletal muscle. At the triad, it colocalizes with calcium calmodulin kinase IIβ (CaMKIIβ). CAPN3 knock out...

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Detalles Bibliográficos
Autores principales: Kramerova, Irina, Torres, Jorge A, Eskin, Ascia, Nelson, Stanley F, Spencer, Melissa J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905633/
https://www.ncbi.nlm.nih.gov/pubmed/29528394
http://dx.doi.org/10.1093/hmg/ddy071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905633/
https://www.ncbi.nlm.nih.gov/pubmed/29528394
http://dx.doi.org/10.1093/hmg/ddy071

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