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Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss

Reactive oxygen species exert important functions in regulating several cellular signalling pathways. However, an excessive accumulation of reactive oxygen species can perturb the redox homeostasis leading to oxidative stress, a condition which has been associated to many neurodegenerative disorders...

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Detalles Bibliográficos
Autores principales: Biosa, Alice, Sanchez-Martinez, Alvaro, Filograna, Roberta, Terriente-Felix, Ana, Alam, Sarah M, Beltramini, Mariano, Bubacco, Luigi, Bisaglia, Marco, Whitworth, Alexander J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905640/
https://www.ncbi.nlm.nih.gov/pubmed/29529199
http://dx.doi.org/10.1093/hmg/ddy069