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Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss
Reactive oxygen species exert important functions in regulating several cellular signalling pathways. However, an excessive accumulation of reactive oxygen species can perturb the redox homeostasis leading to oxidative stress, a condition which has been associated to many neurodegenerative disorders...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905640/ https://www.ncbi.nlm.nih.gov/pubmed/29529199 http://dx.doi.org/10.1093/hmg/ddy069 |