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Brain Cytosolic Phospholipase A(2)α Mediates Angiotensin II-Induced Hypertension and Reactive Oxygen Species Production in Male Mice

BACKGROUND: Recently, we reported that angiotensin II (Ang II)-induced hypertension is mediated by group IV cytosolic phospholipase A(2)α (cPLA(2)α) via production of prohypertensive eicosanoids. Since Ang II increases blood pressure (BP) via its action in the subfornical organ (SFO), it led us to i...

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Detalles Bibliográficos
Autores principales: Song, Chi Young, Khan, Nayaab S, Liao, Francesca-Fang, Wang, Bin, Shin, Ji Soo, Bonventre, Joseph V, Malik, Kafait U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905655/
https://www.ncbi.nlm.nih.gov/pubmed/29342227
http://dx.doi.org/10.1093/ajh/hpy009