Cargando…
Brain Cytosolic Phospholipase A(2)α Mediates Angiotensin II-Induced Hypertension and Reactive Oxygen Species Production in Male Mice
BACKGROUND: Recently, we reported that angiotensin II (Ang II)-induced hypertension is mediated by group IV cytosolic phospholipase A(2)α (cPLA(2)α) via production of prohypertensive eicosanoids. Since Ang II increases blood pressure (BP) via its action in the subfornical organ (SFO), it led us to i...
Autores principales: | Song, Chi Young, Khan, Nayaab S, Liao, Francesca-Fang, Wang, Bin, Shin, Ji Soo, Bonventre, Joseph V, Malik, Kafait U |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905655/ https://www.ncbi.nlm.nih.gov/pubmed/29342227 http://dx.doi.org/10.1093/ajh/hpy009 |
Ejemplares similares
-
6β-Hydroxytestosterone Promotes Angiotensin II-Induced Hypertension via Enhanced Cytosolic Phospholipase A(2)α Activity
por: Singh, Purnima, et al.
Publicado: (2021) -
2-Methoxyestradiol Ameliorates Angiotensin II–Induced Hypertension by Inhibiting Cytosolic Phospholipase A(2)α Activity in Female Mice
por: Song, Chi Young, et al.
Publicado: (2021) -
Ovariectomy Via 12/15-lipoxygenase Augments Angiotensin II-Induced Hypertension and Its Pathogenesis in Female Mice
por: Dutta, Shubha R., et al.
Publicado: (2023) -
Cytosolic Phospholipase A(2)α and Eicosanoids Regulate
Expression of Genes in Macrophages Involved in Host Defense and
Inflammation
por: Suram, Saritha, et al.
Publicado: (2013) -
6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice
por: Pingili, Ajeeth K., et al.
Publicado: (2020)