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Impact of Age-Related Mitochondrial Dysfunction and Exercise on Intestinal Microbiota Composition

Mitochondrial dysfunction is prevalent in the aging gastrointestinal tract. We investigated whether mitochondrial function in aging colonic crypts and exercise influences microbial gut communities in mice. Twelve PolgA(mut)/(mut) mice were randomly divided into a sedentary and exercise group at 4 mo...

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Detalles Bibliográficos
Autores principales: Houghton, David, Stewart, Christopher J, Stamp, Craig, Nelson, Andrew, Aj ami, Nadim J, Petrosino, Joseph F, Wipat, Anil, Trenell, Michael I, Turnbull, Douglass M, Greaves, Laura C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905657/
https://www.ncbi.nlm.nih.gov/pubmed/29045670
http://dx.doi.org/10.1093/gerona/glx197