Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS

Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood. Using genetic loss and gain-of-function analyses in vivo, we show that the conserved MAP3K13 (also known as leucine zi...

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Detalles Bibliográficos
Autores principales: Chen, Meifan, Geoffroy, Cédric G., Meves, Jessica M., Narang, Aarti, Li, Yunbo, Nguyen, Mallorie T., Khai, Vung S., Kong, Xiangmei, Steinke, Christopher L., Carolino, Krislyn I., Elzière, Lucie, Goldberg, Mark P., Jin, Yishi, Zheng, Binhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905706/
https://www.ncbi.nlm.nih.gov/pubmed/29590625
http://dx.doi.org/10.1016/j.celrep.2018.02.102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905706/
https://www.ncbi.nlm.nih.gov/pubmed/29590625
http://dx.doi.org/10.1016/j.celrep.2018.02.102

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