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Leucine Zipper-Bearing Kinase Is a Critical Regulator of Astrocyte Reactivity in the Adult Mammalian CNS
Reactive astrocytes influence post-injury recovery, repair, and pathogenesis of the mammalian CNS. Much of the regulation of astrocyte reactivity, however, remains to be understood. Using genetic loss and gain-of-function analyses in vivo, we show that the conserved MAP3K13 (also known as leucine zi...
Autores principales: | Chen, Meifan, Geoffroy, Cédric G., Meves, Jessica M., Narang, Aarti, Li, Yunbo, Nguyen, Mallorie T., Khai, Vung S., Kong, Xiangmei, Steinke, Christopher L., Carolino, Krislyn I., Elzière, Lucie, Goldberg, Mark P., Jin, Yishi, Zheng, Binhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905706/ https://www.ncbi.nlm.nih.gov/pubmed/29590625 http://dx.doi.org/10.1016/j.celrep.2018.02.102 |
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