Tanshinol borneol ester on nanostructured lipid carriers has longer brain and systemic effector retention and better antioxidant activity in vivo

BACKGROUND: Tanshinol borneol ester (DBZ) is a hybrid of danshensu (DSS) and borneol and has anti-ischemic activity in animals. However, its low water solubility and short half-life limit its clinical application. METHODS: We prepared polyethylene glycol (PEG)-modified and DBZ-loaded nanostructured...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Xinyi, Fei, Fuhuan, Sun, Huanmei, Xiao, Chaoni, Zhao, Xinfeng, Zhang, Yajun, Zheng, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905822/
https://www.ncbi.nlm.nih.gov/pubmed/29695905
http://dx.doi.org/10.2147/IJN.S159789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905822/
https://www.ncbi.nlm.nih.gov/pubmed/29695905
http://dx.doi.org/10.2147/IJN.S159789

Ejemplares similares