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Tanshinol borneol ester on nanostructured lipid carriers has longer brain and systemic effector retention and better antioxidant activity in vivo

BACKGROUND: Tanshinol borneol ester (DBZ) is a hybrid of danshensu (DSS) and borneol and has anti-ischemic activity in animals. However, its low water solubility and short half-life limit its clinical application. METHODS: We prepared polyethylene glycol (PEG)-modified and DBZ-loaded nanostructured...

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Detalles Bibliográficos
Autores principales:	Yuan, Xinyi, Fei, Fuhuan, Sun, Huanmei, Xiao, Chaoni, Zhao, Xinfeng, Zhang, Yajun, Zheng, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905822/ https://www.ncbi.nlm.nih.gov/pubmed/29695905 http://dx.doi.org/10.2147/IJN.S159789

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