The Broad-Spectrum Antimicrobial Potential of [Mn(CO)(4)(S(2)CNMe(CH(2)CO(2)H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization

Aims: Carbon monoxide (CO)-releasing molecules (CORMs) are candidates for animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a novel manganese CORM. Results: [Mn(CO)(4)S(2)CNMe(CH(2)CO(2)H)], CORM-401, inhibits growth of Escherichia coli and several antibiotic-re...

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Detalles Bibliográficos
Autores principales: Wareham, Lauren K., McLean, Samantha, Begg, Ronald, Rana, Namrata, Ali, Salar, Kendall, John J., Sanguinetti, Guido, Mann, Brian E., Poole, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Rebound Original Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905950/
https://www.ncbi.nlm.nih.gov/pubmed/28816060
http://dx.doi.org/10.1089/ars.2017.7239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905950/
https://www.ncbi.nlm.nih.gov/pubmed/28816060
http://dx.doi.org/10.1089/ars.2017.7239

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