Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways

A macromolecular complex of the enzymes involved in human de novo purine biosynthesis, the purinosome, has been shown to consist of a core assembly to regulate the metabolic activity of the pathway. However, it remains elusive whether the core assembly itself can be selectively controlled in the cyt...

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Detalles Bibliográficos
Autores principales: Schmitt, Danielle L., Sundaram, Anand, Jeon, Miji, Luu, Bao Tran, An, Songon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905998/
https://www.ncbi.nlm.nih.gov/pubmed/29668719
http://dx.doi.org/10.1371/journal.pone.0195989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905998/
https://www.ncbi.nlm.nih.gov/pubmed/29668719
http://dx.doi.org/10.1371/journal.pone.0195989

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