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Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways
A macromolecular complex of the enzymes involved in human de novo purine biosynthesis, the purinosome, has been shown to consist of a core assembly to regulate the metabolic activity of the pathway. However, it remains elusive whether the core assembly itself can be selectively controlled in the cyt...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905998/ https://www.ncbi.nlm.nih.gov/pubmed/29668719 http://dx.doi.org/10.1371/journal.pone.0195989 |