Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers

BACKGROUND: Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP) of V. cholerae are involved in mediating protecti...

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Detalles Bibliográficos
Autores principales: Islam, Kamrul, Hossain, Motaher, Kelly, Meagan, Mayo Smith, Leslie M., Charles, Richelle C., Bhuiyan, Taufiqur Rahman, Kováč, Pavol, Xu, Peng, LaRocque, Regina C., Calderwood, Stephen B., Simon, Jakub K., Chen, Wilbur H., Haney, Douglas, Lock, Michael, Lyon, Caroline E., Kirkpatrick, Beth D., Cohen, Mitchell, Levine, Myron M., Gurwith, Marc, Harris, Jason B., Qadri, Firdausi, Ryan, Edward T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906022/
https://www.ncbi.nlm.nih.gov/pubmed/29624592
http://dx.doi.org/10.1371/journal.pntd.0006376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906022/
https://www.ncbi.nlm.nih.gov/pubmed/29624592
http://dx.doi.org/10.1371/journal.pntd.0006376

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