Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo exposure to highly effective trypanocidal compounds prompted us to explore the potential for dormancy and its contribution to failed drug treatments in this infection. We document the development of non-proliferatin...

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Detalles Bibliográficos
Autores principales: Sánchez-Valdéz, Fernando J, Padilla, Angel, Wang, Wei, Orr, Dylan, Tarleton, Rick L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906098/
https://www.ncbi.nlm.nih.gov/pubmed/29578409
http://dx.doi.org/10.7554/eLife.34039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906098/
https://www.ncbi.nlm.nih.gov/pubmed/29578409
http://dx.doi.org/10.7554/eLife.34039

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