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Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure
The ability of the Chagas disease agent Trypanosoma cruzi to resist extended in vivo exposure to highly effective trypanocidal compounds prompted us to explore the potential for dormancy and its contribution to failed drug treatments in this infection. We document the development of non-proliferatin...
Autores principales: | Sánchez-Valdéz, Fernando J, Padilla, Angel, Wang, Wei, Orr, Dylan, Tarleton, Rick L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906098/ https://www.ncbi.nlm.nih.gov/pubmed/29578409 http://dx.doi.org/10.7554/eLife.34039 |
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