αA-crystallin-derived minichaperone stabilizes αAG98R-crystallin by affecting its zeta potential

PURPOSE: The G98R mutant of αA-crystallin is associated with the development of presenile cataracts. In vitro, the recombinant mutant protein exhibits altered structural and functional characteristics, along with the propensity to aggregate by itself and precipitate. Previously, we have reported tha...

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Detalles Bibliográficos
Autores principales: Phadte, Ashutosh S., Santhoshkumar, Puttur, Sharma, K. Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906106/
https://www.ncbi.nlm.nih.gov/pubmed/29706763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906106/
https://www.ncbi.nlm.nih.gov/pubmed/29706763

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