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αA-crystallin-derived minichaperone stabilizes αAG98R-crystallin by affecting its zeta potential
PURPOSE: The G98R mutant of αA-crystallin is associated with the development of presenile cataracts. In vitro, the recombinant mutant protein exhibits altered structural and functional characteristics, along with the propensity to aggregate by itself and precipitate. Previously, we have reported tha...
Autores principales: | Phadte, Ashutosh S., Santhoshkumar, Puttur, Sharma, K. Krishna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906106/ https://www.ncbi.nlm.nih.gov/pubmed/29706763 |
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