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Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis

In Drosophila, the JNK pathway eliminates by apoptosis aberrant cells that appear in development. It also performs other functions associated with cell proliferation, but analysis of the latter is hindered by the pro-apoptotic activity. We report the response of apoptosis-deficient cells to transien...

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Detalles Bibliográficos
Autores principales: Pinal, Noelia, Martín, María, Medina, Izarne, Morata, Ginés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906466/
https://www.ncbi.nlm.nih.gov/pubmed/29670104
http://dx.doi.org/10.1038/s41467-018-04000-6