TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs’ functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the first 20q-TERRA knockout models and to demonstrate t...

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Detalles Bibliográficos
Autores principales: Montero, Juan J., López-Silanes, Isabel, Megías, Diego, F. Fraga, Mario, Castells-García, Álvaro, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906467/
https://www.ncbi.nlm.nih.gov/pubmed/29670078
http://dx.doi.org/10.1038/s41467-018-03916-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906467/
https://www.ncbi.nlm.nih.gov/pubmed/29670078
http://dx.doi.org/10.1038/s41467-018-03916-3

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