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TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin
TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs’ functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the first 20q-TERRA knockout models and to demonstrate t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906467/ https://www.ncbi.nlm.nih.gov/pubmed/29670078 http://dx.doi.org/10.1038/s41467-018-03916-3 |