Synthesis of novel ligands targeting phenazine biosynthesis proteins as a strategy for antibiotic intervention

ABSTRACT: In this contribution, we report synthetic strategies towards potential ligands for the study of binding differences between PhzE, the first enzyme in the biosynthesis of phenazines, and the related enzyme anthranilate synthase. The ligands were designed with the overriding goal to develop...

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Detalles Bibliográficos
Autores principales: Guttenberger, Nikolaus, Schlatzer, Thomas, Leypold, Mario, Tassoti, Sebastian, Breinbauer, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906492/
https://www.ncbi.nlm.nih.gov/pubmed/29681660
http://dx.doi.org/10.1007/s00706-017-2100-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906492/
https://www.ncbi.nlm.nih.gov/pubmed/29681660
http://dx.doi.org/10.1007/s00706-017-2100-z

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