Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22

Resolution-phase macrophage population orchestrates active dampening of the inflammation by secreting anti-inflammatory and proresolving products including interleukin (IL)-10 and lipid mediators (LMs). We investigated the effects of both human bone marrow-derived mesenchymal stromal cells (MSCs) an...

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Detalles Bibliográficos
Autores principales: Hyvärinen, Kati, Holopainen, Minna, Skirdenko, Vita, Ruhanen, Hanna, Lehenkari, Petri, Korhonen, Matti, Käkelä, Reijo, Laitinen, Saara, Kerkelä, Erja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906545/
https://www.ncbi.nlm.nih.gov/pubmed/29706969
http://dx.doi.org/10.3389/fimmu.2018.00771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906545/
https://www.ncbi.nlm.nih.gov/pubmed/29706969
http://dx.doi.org/10.3389/fimmu.2018.00771

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