A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis

BACKGROUND: Collagen XI (CXI) is a heterotrimeric molecule with triple helical structure in which the α3(XI) chain is identical to the α1(II) chain of collagen II (CII), but with extensive posttranslational modifications. CXI molecules are intermingled in the cartilage collagen fibers, which are mai...

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Detalles Bibliográficos
Autores principales: Tong, Dongmei, Lönnblom, Erik, Yau, Anthony C. Y., Nandakumar, Kutty Selva, Liang, Bibo, Ge, Changrong, Viljanen, Johan, Li, Lei, Bãlan, Mirela, Klareskog, Lars, Chagin, Andrei S., Gjertsson, Inger, Kihlberg, Jan, Zhao, Ming, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906551/
https://www.ncbi.nlm.nih.gov/pubmed/29706949
http://dx.doi.org/10.3389/fimmu.2018.00451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906551/
https://www.ncbi.nlm.nih.gov/pubmed/29706949
http://dx.doi.org/10.3389/fimmu.2018.00451

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