c-Jun-mediated microRNA-302d-3p induces RPE dedifferentiation by targeting p21(Waf1/Cip1)

Dedifferentiation of retinal pigment epithelium (RPE) cells and choroidal neovascularization (CNV) contributes to the pathogenesis of age-related macular degeneration (AMD). MicroRNAs (miRNAs) have crucial roles in AMD onset and progression. We thus aim to investigate the effects of miRNAs on RPE de...

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Detalles Bibliográficos
Autores principales: Jiang, Chao, Xie, Ping, Sun, Ruxu, Sun, Xiantao, Liu, Guohua, Ding, Sijia, Zhu, Meidong, Yan, Biao, Liu, Qinghuai, Chen, Xue, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906557/
https://www.ncbi.nlm.nih.gov/pubmed/29670082
http://dx.doi.org/10.1038/s41419-018-0481-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906557/
https://www.ncbi.nlm.nih.gov/pubmed/29670082
http://dx.doi.org/10.1038/s41419-018-0481-5

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