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c-Jun-mediated microRNA-302d-3p induces RPE dedifferentiation by targeting p21(Waf1/Cip1)
Dedifferentiation of retinal pigment epithelium (RPE) cells and choroidal neovascularization (CNV) contributes to the pathogenesis of age-related macular degeneration (AMD). MicroRNAs (miRNAs) have crucial roles in AMD onset and progression. We thus aim to investigate the effects of miRNAs on RPE de...
Autores principales: | Jiang, Chao, Xie, Ping, Sun, Ruxu, Sun, Xiantao, Liu, Guohua, Ding, Sijia, Zhu, Meidong, Yan, Biao, Liu, Qinghuai, Chen, Xue, Zhao, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906557/ https://www.ncbi.nlm.nih.gov/pubmed/29670082 http://dx.doi.org/10.1038/s41419-018-0481-5 |
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