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Early Lymphocyte Loss and Increased Granulocyte/Lymphocyte Ratio Predict Systemic Spread of Streptococcus pyogenes in a Mouse Model of Acute Skin Infection

Background: Group A streptococci may induce lymphopenia, but the value of lymphocyte loss as early biomarkers for systemic spread and severe infection has not been examined systematically. Methods: We evaluated peripheral blood cell indices as biomarkers for severity and spread of infection in a mou...

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Detalles Bibliográficos
Autores principales: Loof, Torsten G., Sohail, Aaqib, Bahgat, Mahmoud M., Tallam, Aravind, Arshad, Haroon, Akmatov, Manas K., Pils, Marina C., Heise, Ulrike, Beineke, Andreas, Pessler, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906586/
https://www.ncbi.nlm.nih.gov/pubmed/29707522
http://dx.doi.org/10.3389/fcimb.2018.00101