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Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer

The loss of p300/CBP-associated protein (PCAF) expression is associated with poor clinical outcome in gastric cancer, and a potential bio-marker for invasive and aggressive tumors. However, the mechanism linking loss of PCAF to the onset of gastric cancer has not been identified. Given that PCAF and...

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Detalles Bibliográficos
Autores principales: Brasacchio, Daniella, Busuttil, Rita A., Noori, Tahereh, Johnstone, Ricky W., Boussioutas, Alex, Trapani, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906598/
https://www.ncbi.nlm.nih.gov/pubmed/29670108
http://dx.doi.org/10.1038/s41419-018-0470-8