Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice

Pancreatic ductal adenocarcinoma (PDA) has a 5-year survival rate of less than 5% and is the sixth leading cause of cancer death. Although KRAS mutations are one of the major driver mutations in PDA, KRAS mutation alone is not sufficient to induce invasive pancreatic cancer in mice model. HER2, also...

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Detalles Bibliográficos
Autores principales: Shibata, Wataru, Kinoshita, Hiroto, Hikiba, Yohko, Sato, Takeshi, Ishii, Yasuaki, Sue, Soichiro, Sugimori, Makoto, Suzuki, Nobumi, Sakitani, Kosuke, Ijichi, Hideaki, Mori, Ryutaro, Endo, Itaru, Maeda, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906617/
https://www.ncbi.nlm.nih.gov/pubmed/29670173
http://dx.doi.org/10.1038/s41598-018-24375-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906617/
https://www.ncbi.nlm.nih.gov/pubmed/29670173
http://dx.doi.org/10.1038/s41598-018-24375-2

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