Anticoagulant mechanism, pharmacological activity, and assessment of preclinical safety of a novel fibrin(ogen)olytic serine protease from leaves of Leucas indica

The harnessing of medicinal plants containing a plethora of bioactive molecules may lead to the discovery of novel, potent and safe therapeutic agents to treat thrombosis-associated cardiovascular diseases. A 35 kDa (m/z 34747.5230) serine protease (lunathrombase) showing fibrin(ogen)olytic activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Gogoi, Debananda, Arora, Neha, Kalita, Bhargab, Sarma, Rahul, Islam, Taufikul, Ghosh, Sidhhartha S., Devi, Rajlakshmi, Mukherjee, Ashis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906637/
https://www.ncbi.nlm.nih.gov/pubmed/29670183
http://dx.doi.org/10.1038/s41598-018-24422-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906637/
https://www.ncbi.nlm.nih.gov/pubmed/29670183
http://dx.doi.org/10.1038/s41598-018-24422-y

Ejemplares similares