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REST, regulated by RA through miR-29a and the proteasome pathway, plays a crucial role in RPC proliferation and differentiation

One of the primary obstacles in the application of retinal progenitor cells (RPCs) to the treatment of retinal degenerative diseases, such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP), is their limited ability to proliferate and differentiate into specific retinal neurons....

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Detalles Bibliográficos
Autores principales: Wang, Yuyao, Zhang, Dandan, Tang, Zhimin, Zhang, Yi, Gao, Huiqin, Ni, Ni, Shen, Bingqiao, Sun, Hao, Gu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906654/
https://www.ncbi.nlm.nih.gov/pubmed/29670089
http://dx.doi.org/10.1038/s41419-018-0473-5