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Structure and Properties of DNA Molecules Over The Full Range of Biologically Relevant Supercoiling States

Topology affects physical and biological properties of DNA and impacts fundamental cellular processes, such as gene expression, genome replication, chromosome structure and segregation. In all organisms DNA topology is carefully modulated and the supercoiling degree of defined genome regions may cha...

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Detalles Bibliográficos
Autores principales: Bettotti, Paolo, Visone, Valeria, Lunelli, Lorenzo, Perugino, Giuseppe, Ciaramella, Maria, Valenti, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906655/
https://www.ncbi.nlm.nih.gov/pubmed/29670174
http://dx.doi.org/10.1038/s41598-018-24499-5