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Loss of DEPTOR in renal tubules protects against cisplatin-induced acute kidney injury

DEP domain containing mTOR-interacting protein (DEPTOR) was originally identified as an in vivo dual inhibitor of mechanistic target of rapamycin (mTOR). It was recently reported to be involved in renal physiology and pathology in vitro; however, its detailed roles and mechanisms in vivo are complet...

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Detalles Bibliográficos
Autores principales: Wang, Caixia, Dai, Huaiqian, Xiong, Zhi, Song, Qiancheng, Zou, Zhipeng, Li, Mangmang, Nie, Jing, Bai, Xiaochun, Chen, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906659/
https://www.ncbi.nlm.nih.gov/pubmed/29670094
http://dx.doi.org/10.1038/s41419-018-0483-3