Inhibition of cyclin-dependent kinase 4 as a potential therapeutic strategy for treatment of synovial sarcoma

Synovial sarcoma is a highly aggressive but rare form of soft tissue malignancy that primarily affects the extremities of the arms or legs, for which current chemotherapeutic agents have not been proven to be very effective. The cyclin-dependent kinase 4/6-retinoblastoma protein (CDK4/6-Rb) pathway...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyang, Seebacher, Nicole A., Garbutt, Cassandra, Ma, Hangzhan, Gao, Peng, Xiao, Tao, Hornicek, Francis J., Duan, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906661/
https://www.ncbi.nlm.nih.gov/pubmed/29670090
http://dx.doi.org/10.1038/s41419-018-0474-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906661/
https://www.ncbi.nlm.nih.gov/pubmed/29670090
http://dx.doi.org/10.1038/s41419-018-0474-4

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