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UDP-sugars activate P2Y(14) receptors to mediate vasoconstriction of the porcine coronary artery

AIMS: UDP-sugars can act as extracellular signalling molecules, but relatively little is known about their cardiovascular actions. The P2Y(14) receptor is a G(i/o)-coupled receptor which is activated by UDP-glucose and related sugar nucleotides. In this study we sought to investigate whether P2Y(14)...

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Detalles Bibliográficos
Autores principales: Abbas, Zainab S.B., Latif, M. Liaque, Dovlatova, Natalia, Fox, Sue C., Heptinstall, Stan, Dunn, William R., Ralevic, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906693/
https://www.ncbi.nlm.nih.gov/pubmed/29253618
http://dx.doi.org/10.1016/j.vph.2017.12.063