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Effect of Postmortem Interval and Years in Storage on RNA Quality of Tissue at a Repository of the NIH NeuroBioBank

Brain tissue from 1068 donors was analyzed for RNA quality as a function of postmortem interval (PMI) and years in storage. Approximately 83% of the cortical and cerebellar samples had an RNA integrity number (RIN) of 6 or greater, indicating their likely suitability for real-time quantitative polym...

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Detalles Bibliográficos
Autores principales: White, Kimberly, Yang, Peixin, Li, Ling, Farshori, Amna, Medina, Alexandre E., Zielke, Horst Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906728/
https://www.ncbi.nlm.nih.gov/pubmed/29498539
http://dx.doi.org/10.1089/bio.2017.0099