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Regulation of Kv4.3 and hERG potassium channels by KChIP2 isoforms and DPP6 and response to the dual K(+) channel activator NS3623
Transient outward potassium current (I(to)) contributes to early repolarization of many mammalian cardiac action potentials, including human, whilst the rapid delayed rectifier K(+) current (I(Kr)) contributes to later repolarization. Fast I(to) channels can be produced from the Shal family KCNDE ge...
Autores principales: | Lainez, Sergio, Doray, Adélaïde, Hancox, Jules C., Cannell, Mark B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906734/ https://www.ncbi.nlm.nih.gov/pubmed/29378180 http://dx.doi.org/10.1016/j.bcp.2018.01.036 |
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