Transcription Factor SOX5 Promotes the Migration and Invasion of Fibroblast-Like Synoviocytes in Part by Regulating MMP-9 Expression in Collagen-Induced Arthritis

OBJECTIVES: Fibroblast-like synoviocytes (FLS) exhibit a unique aggressive phenotype in rheumatoid arthritis (RA). Increased FLS migration and subsequent invasion of the extracellular matrix are essential to joint destruction in RA. Our previous research reported that transcription factor SOX5 was h...

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Detalles Bibliográficos
Autores principales: Shi, Yumeng, Wu, Qin, Xuan, Wenhua, Feng, Xiaoke, Wang, Fang, Tsao, Betty P., Zhang, Miaojia, Tan, Wenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906798/
https://www.ncbi.nlm.nih.gov/pubmed/29706965
http://dx.doi.org/10.3389/fimmu.2018.00749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906798/
https://www.ncbi.nlm.nih.gov/pubmed/29706965
http://dx.doi.org/10.3389/fimmu.2018.00749

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