Modeling and correct the GC bias of tumor and normal WGS data for SCNA based tumor subclonal population inferring

BACKGROUND: Somatic copy number alternations (SCNAs) can be utilized to infer tumor subclonal populations in whole genome seuqncing studies, where usually their read count ratios between tumor-normal paired samples serve as the inferring proxy. Existing SCNA based subclonal population inferring tool...

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Detalles Bibliográficos
Autores principales: Chu, Yanshuo, Teng, Mingxiang, Wang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907144/
https://www.ncbi.nlm.nih.gov/pubmed/29671389
http://dx.doi.org/10.1186/s12859-018-2099-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907144/
https://www.ncbi.nlm.nih.gov/pubmed/29671389
http://dx.doi.org/10.1186/s12859-018-2099-0

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