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Modeling and correct the GC bias of tumor and normal WGS data for SCNA based tumor subclonal population inferring
BACKGROUND: Somatic copy number alternations (SCNAs) can be utilized to infer tumor subclonal populations in whole genome seuqncing studies, where usually their read count ratios between tumor-normal paired samples serve as the inferring proxy. Existing SCNA based subclonal population inferring tool...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907144/ https://www.ncbi.nlm.nih.gov/pubmed/29671389 http://dx.doi.org/10.1186/s12859-018-2099-0 |