Annotating activation/inhibition relationships to protein-protein interactions using gene ontology relations

BACKGROUND: Signaling pathways can be reconstructed by identifying ‘effect types’ (i.e. activation/inhibition) of protein-protein interactions (PPIs). Effect types are composed of ‘directions’ (i.e. upstream/downstream) and ‘signs’ (i.e. positive/negative), thereby requiring directions as well as si...

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Detalles Bibliográficos
Autores principales: Yim, Soorin, Yu, Hasun, Jang, Dongjin, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907154/
https://www.ncbi.nlm.nih.gov/pubmed/29671402
http://dx.doi.org/10.1186/s12918-018-0535-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907154/
https://www.ncbi.nlm.nih.gov/pubmed/29671402
http://dx.doi.org/10.1186/s12918-018-0535-4

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