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Endoplasmic reticulum stress in perivascular adipose tissue promotes destabilization of atherosclerotic plaque by regulating GM-CSF paracrine

BACKGROUND: Perivascular adipose tissue (PVAT) accelerates plaque progression and increases cardiovascular risk. We tested the hypothesis that PVAT contributed to plaque vulnerability and investigated whether endoplasmic reticulum stress (ER stress) in PVAT played an important role in vulnerable pla...

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Detalles Bibliográficos
Autores principales: Ying, Ru, Li, Sheng-Wei, Chen, Jia-Yuan, Zhang, Hai-Feng, Yang, Ying, Gu, Zhen-Jie, Chen, Yang-Xin, Wang, Jing-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907173/
https://www.ncbi.nlm.nih.gov/pubmed/29669585
http://dx.doi.org/10.1186/s12967-018-1481-z