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Endoplasmic reticulum stress in perivascular adipose tissue promotes destabilization of atherosclerotic plaque by regulating GM-CSF paracrine
BACKGROUND: Perivascular adipose tissue (PVAT) accelerates plaque progression and increases cardiovascular risk. We tested the hypothesis that PVAT contributed to plaque vulnerability and investigated whether endoplasmic reticulum stress (ER stress) in PVAT played an important role in vulnerable pla...
Autores principales: | Ying, Ru, Li, Sheng-Wei, Chen, Jia-Yuan, Zhang, Hai-Feng, Yang, Ying, Gu, Zhen-Jie, Chen, Yang-Xin, Wang, Jing-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907173/ https://www.ncbi.nlm.nih.gov/pubmed/29669585 http://dx.doi.org/10.1186/s12967-018-1481-z |
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