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Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis

BACKGROUND: The success of clinical trials of selective B cell depletion in patients with relapsing multiple sclerosis (MS) indicates B cells are important contributors to peripheral immune responses involved in the development of new relapses. Such B cell contribution to peripheral inflammation lik...

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Detalles Bibliográficos
Autores principales: Touil, Hanane, Kobert, Antonia, Lebeurrier, Nathalie, Rieger, Aja, Saikali, Philippe, Lambert, Caroline, Fawaz, Lama, Moore, Craig S., Prat, Alexandre, Gommerman, Jennifer, Antel, Jack P., Itoyama, Yasuto, Nakashima, Ichiro, Bar-Or, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907187/
https://www.ncbi.nlm.nih.gov/pubmed/29673365
http://dx.doi.org/10.1186/s12974-018-1136-2